
Afobazole hydrochloride
CAS No. 173352-39-1
Afobazole hydrochloride( CM346 hydrochloride )
Catalog No. M17367 CAS No. 173352-39-1
Fabomotizole HCl (CM346 HCl), an anxiolytic drug, produces anxiolytic and neuroprotective effects.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 104 | Get Quote |
![]() ![]() |
25MG | 345 | Get Quote |
![]() ![]() |
50MG | 417 | Get Quote |
![]() ![]() |
100MG | 613 | Get Quote |
![]() ![]() |
200MG | Get Quote | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameAfobazole hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionFabomotizole HCl (CM346 HCl), an anxiolytic drug, produces anxiolytic and neuroprotective effects.
-
DescriptionFabomotizole HCl (CM346 HCl), an anxiolytic drug, produces anxiolytic and neuroprotective effects. The mechanism of Afobazole remains poorly defined, however, with GABAergic, NGF, and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole inhibits MAO-A reversibly and there might be also some involvement with serotonin receptors.(In Vitro):Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.
-
In VitroAfobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.
-
In Vivo——
-
SynonymsCM346 hydrochloride
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorOthers
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number173352-39-1
-
Formula Weight343.87
-
Molecular FormulaC15H22ClN3O2S
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 44 mg/mL 127.96 mM
-
SMILESCCOc1cc2c(cc1)nc([nH]2)SCCN1CCOCC1.Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Afobazole, From Wikipedia
molnova catalog



related products
-
Carmofur
Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal Y.
-
TMPyP4 tosylate
TMPyP4 tosylate is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.
-
1,4-Dideoxy-1,4-epit...
1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity.1,4-Dideoxy-1,4-epithio-D-ribitol induces apoptosis through inhibition of DNA synthesis.